REACT System - Advanced Traction for Endoscopic Submucosal Dissection
Repositionable Elastic Adaptive Customisable Traction
A revolutionary multipoint traction system for endoscopic submucosal dissection (ESD) that enhances procedural safety and efficacy through customizable elastic bands.
Key Features of REACT Traction System for ESD
Repositionable
Easily adjust traction points during the procedure without interrupting workflow
Adaptive
Automatically adjusts tension based on tissue resistance and procedural needs
Customizable
Multiple band configurations to suit different anatomical locations and lesion types
Clinical Study Results: REACT System Safety and Efficacy
Ghent University Hospital Study (2023-2025)
Study Design
- - 40 colorectal lesions (20mm or larger)
- - 22-month observation period
- - Tertiary referral center
- - Median lesion size: 30mm
Key Outcomes
- - 90% R0 resection rate
- - 95% improved submucosal access
- - 17.6 mm2/min median dissection speed
- - 97.5% en-bloc resection rate
Safety Profile
- ✓All perforations managed conservatively
- ✓No surgical interventions required
- ✓No delayed perforations observed
- ✓Comparable to established traction methods
Procedural Benefits
- ✓5.5 minute median deployment time
- ✓Real-time adjustability during procedure
- ✓97.5% en-bloc resection rate
- ✓Low device failure rate (1.3% clip detachment)
REACT System Technical Specifications & Materials
Materials
Elastic Bands
Medical-grade latex (Fox 1/4 inch 3.5Oz, Ormco)
Attachment Method
Re-openable rotatable clips (ScopeClip, Creo Medical)
Connection System
Cow hitch knots for secure band linkage
Configuration Options
REACT-3
3 traction bands - small lesions (47.5% usage)
REACT-4
4 traction bands - medium lesions (32.5% usage)
REACT-5 & REACT-6
5-6 traction bands - large/complex lesions
Color-Coding System
Purple
Fixation Band
Green
Linking Band
Pink
Traction Bands
Orange
Traction Bands
REACT System Video: Colorectal ESD Procedure Demonstration
Watch the REACT-6 system being deployed during a colorectal ESD procedure
Procedural Applications & Techniques
Deployment Protocol
- 1
Lesion Preparation
Circumferential incision with partial trimming for mucosal flap mobility
- 2
REACT Introduction
Grasp traction band with re-openable clip, pull into endoscope cap
- 3
Sequential Attachment
Attach traction bands evenly around lesion margin, perpendicular to edge
- 4
Fixation
Attach fixation band to opposite colonic wall above lesion midpoint
Dynamic Adjustment
Real-time repositioning of bands and modification of traction direction as needed
Anatomical Coverage
52.5% rectal, 22.5% sigmoid, 15% transverse colon lesions successfully treated
Rapid Deployment
Median deployment time of 5 minutes 33 seconds with minimal training required
Advantages Over Traditional Methods
| Feature | REACT | ATRACT | Clip-with-Line | S-O Clip |
|---|---|---|---|---|
| Traction Points | Multiple (3-6) | Multiple | Single | Single |
| Adjustability | Real-time repositioning | Adaptive tension | Limited | Fixed |
| Material Cost | Low (~$5) | High | Low | High |
| Special Equipment | None required | Proprietary device | None | Proprietary device |
| Assembly Time | < 2 minutes | Pre-assembled | Variable | Pre-assembled |
| Reported Speed | 17.6 mm²/min | 37.4 mm²/min | Not specified | Not specified |
REACT System Research Publications & Clinical Trials
Published Clinical Study
REACT Multipoint Elastic Traction for Colorectal ESD: A Retrospective Single-Center Feasibility Series of 59 Consecutive Cases
Poortmans PJ, Montori M, Debels LK, Argenziano ME, Botelberge T, Hoorens A, Smeets S, Sorge A, Tornai T, Desomer L, Tate DJ
Gastrointestinal Endoscopy, • DOI: 10.1016/j.gie.2025.12.273
Abstract
Background and Aims: Effective traction for endoscopic submucosal dissection (ESD) should be applicable to diverse lesion morphologies and locations, adapting as dissection progresses, allow repositioning and be cost-effective. To meet these criteria we developed Repositionable Elastic Adaptive Customizable Traction (REACT), a customizable, low-cost multipoint traction method assembled from orthodontic elastic bands. This study aimed to evaluate the safety and feasibility of REACT-assisted ESD in a retrospective colorectal series.
Study Authors
- • Poortmans PJ - University Hospital Ghent
- • Montori M - Università Politecnica delle Marche
- • Debels LK - University Hospital Ghent
- • Argenziano ME, Botelberge T, Hoorens A
- • Smeets S, Sorge A, Tornai T, Desomer L
- • Tate DJ - University Hospital Ghent
Study Details
- Design: Retrospective single-center series
- Cases: 59 consecutive colorectal ESDs
- Center: University Hospital Ghent, Belgium
- Journal: Gastrointestinal Endoscopy (Elsevier)
Contact Us: REACT System Training and Implementation
Join leading endoscopy centers worldwide in adopting this innovative traction system
Department of Gastroenterology and Hepatology
University Hospital Ghent - C. Heymanslaan 10 -B-9000 Gent,Belgium